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Crestor has shown significant improvements in cholesterol at a low dose.11

As well as potentially cutting LDL cholesterol by half,1,3,5,7-11 Crestor has also been shown to get 8 out of 10 patients to their LDL target on the usual starting dose of 10mg.5


Why is this so important
High LDL cholesterol is directly linked to heart disease and stroke. Evidence shows for every one standard unit reduction in LDL, your relative risk of cardiovascular events is reduced by approximately 20%.6

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Diagram: How Effective Is Crestor

This link was recently demonstrated in the large JUPITER trial of 18,000 patients with no history of previous cardiovascular events, who had low to moderate LDL (bad) cholesterol.* Crestor reduced LDL by 50%, and also reduced the relative risk of major cardiovascular events by 44%. Major cardiovascular events were defined as any of the following:

  • » Myocardial infarction (heart attack)
  • » Stroke
  • » Unstable angina
  • » Death from cardiovascular causes
  • » Arterial revascularisation (surgery to restore impaired blood flow to the heart)

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*Patients were enrolled if their LDL <3.4mmol/L. At baseline the mean LDL was 2.8mmol/L.


Crestor Delivers

  • » Crestor 10mg gets 8 out of 10 patients to their LDL goal5
  • » Crestor 10mg can cut LDL in half 1,3,5,7-11
  • » Crestor has a positive effect on HDL-C (good cholesterol) which is maintained across the dose range111
  • » Crestor generally provides 90% of its maximum cholesterol lowering response within 2 weeks11
  • » Crestor is well tolerated11

Crestor Experience
Crestor is approved in over 95 countries. More than 240 million prescriptions have been written for Crestor worldwide.12

Crestor Study Programme
More than 65,000 patients have been recruited from more than 55 countries worldwide to participate in the GALAXY Program of clinical studies.12